Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Average daily step count reflects disability in MS

Key clinical point: Average daily step count may be a surrogate measure of disability in MS.

Major finding: Mean daily step count was correlated with Expanded Disability Status Scale, timed 25-foot walk performance, Physical Health Composite score, and Symbol Digit Modalities Test score.

Study details: A prospective, phase 3 trial of 492 patients with inactive progressive MS.

Disclosures: The presenter received reimbursement for travel expenses related to this study from MedDay Pharmaceuticals. Coinvestigators received research support and compensation from companies such as Abbvie, Alexion, Biogen, Genentech, MedDay Pharmaceuticals, Novartis, and Sanofi Genzyme. One investigator is an employee of MedDay Pharmaceuticals.


Block V et al. ECTRIMS 2019, Abstract 217.