Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Out-of-Pocket Costs for Neurologic Medications Rise Sharply

Key clinical point: Out-of-pocket costs for medications to treat neurologic conditions increased sharply between 2004 and 2016.

Major finding: The out-of-pocket cost of multiple sclerosis (MS) treatments increased the most, with a 20-fold increase during that time.

Study details: An analysis of data from more than 900,000 patients with neurologic conditions in a large, privately insured health care claims database.

Disclosures: The study was supported by the American Academy of Neurology. Several authors are supported by National Institutes of Health grants. Dr. Callaghan receives research support from Impeto Medical and performs consulting work.


Callaghan BC et al. Neurology. 2019 May 1. doi: 10.1212/WNL.0000000000007564.