Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Must Reads by Date

Must reads for theWeek ending July 10, 2016

Location-Specific Gray Matter Loss and Disability , JAMA Neurology; ePub 2016 Jun 13; Mackenzie-Graham, et al

Primary Process in MS Lesions Likely Tissue Loss, Mult Scler; ePub 2016 Jun 23; Sethi, Nair, et al

Co-Occurring Impairments and Job Loss Risk , Clin Neuropsychol; 2016 Jun 21; Frndak, et al

Abbreviated Neuropsychological Tests Prove Valid, Clin Neuropsychol; ePub 2016 Jun 9; Gromisch, et al

Ocrelizumab Beneficial in Immune Suppression, Curr Opin Neurol; 2016 Jun; Steinman, Zamvil

More must reads

Must reads for theWeek ending July 3, 2016

Incident Dementia & Hematoma Size, Location Linked, JAMA Neurology; ePub 2016 Jun 13; Biffi, Bailey, et al

Cardio Fitness Inversely Linked with Stroke Risk, Stroke; ePub 2016 Jun 9; Pandey, Patel, et al

Hyperammonemia and Generalized Seizures Linked, Epilepsia; ePub 2016 Jun 1; Albadareen, et al

Cluster Headache Electronic Records Compromised, Headache; ePub 2016 Jun 6; Rizzoli, Loder, et al

Clinical Stem-Cell Trial for MS Looks Promising, Lancet; ePub 2016 Jun 9; Atkins, Bowman, et al

More must reads

Must reads for theWeek ending June 26, 2016

Genetic Risk Burden Linked with Disease Phenotypes, JAMA Neurology; ePub 2016 May 31; Isobe, et al

MS-Associated Tremor Remains Poorly Treated, Int J MS Care; 2016 May-June; Meadow, et al

Discontinuing Disease-Modifying Therapy in MS, Int J MS Care; ePub 2016 May 19; Birnbaum

Stopping Inflammation Reduces Secondary Atrophy, Mult Scler J; ePub 2016 May 31; Lee, Narayanan, et al

Mapping Study Characterizes MS Lesion Changes, AJNR Am J Neuroradiol; ePub 2016 Jun 2; Zhang, et al

More must reads

Must reads for theWeek ending June 19, 2016

Consistent Link Found Between Migraine, CVD, BMJ; ePub 2016 May 31; Kurth, Winter, et al

Migraine-Specific Hormone Profiles Discovered, Neurology; ePub 2016 Jun 1; Pavlović, Allshouse, et al

Cerebral Microbleeds Linked with Dementia, JAMA Neurol; ePub 2016 Jun 6; Akoudad, et al

Fragmentation Doesn’t Explain Total Sleep Time, J Clin Sleep Med; ePub 2016 May 25; Saline, et al

Low BDNF, Cognitive Decline Linked in Parkinson, Parkinsonism Relat Disord; ePub 2016 May 24; Wang, et al

More must reads

Must reads for theWeek ending June 12, 2016

FDA Approves ZINBRYTA for Multiple Sclerosis, Biogen, AbbVie news release; 2016 May 27

MS Comorbidities Impact Clinical Outcomes, Mult Scler J; ePub 2016 May 26; Conway, et al

Evaluating Information Processing Speed in MS, Mult Scler J; ePub 2016 May 9; Costa, et al

2 Therapies Show No Increased Depression in MS, J Neurol; ePub 2016 May 13; Schippling, et al

Frontal Perfusion Deficits Found in MS Patients, AJNR Am J Neuroradiol; ePub 2016 May 19; Vitorino, et al

More must reads

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