Frequent episodes of weakness and fatigue
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Krupa Pandey, MD, Director, Multiple Sclerosis Center, Department of Neurology & Neuroscience Institute, Hackensack University Medical Center; Neurologist, Department of Neurology, Hackensack Meridian Health, Hackensack, NJ

Krupa Pandey, MD, has serve(d) as a speaker or a member of a speakers bureau for: Bristol-Myers Squibb; Biogen; Alexion; Genentech; Sanofi-Genzyme

Question 1 of 3

A 29-year-old woman was referred to the neurology clinic by her internist after experiencing frequent episodes of weakness, fatigue, and a tingling sensation in different areas of her body. Then, the patient abruptly developed a right hemisensory deficit about 2 months ago and has been feeling progressively worse. MRI revealed multifocal white matter disease with areas of increased T2 signaling in both cerebral hemispheres with the presence of gadolinium enhancement in three of the lesions. Spinal tap revealed the presence of oligoclonal bands in cerebrospinal fluid (CSF). Visual evoked response testing was abnormal, with slowed conduction in optic nerves.

Can you determine yet whether this patient has multiple sclerosis (MS) or clinically isolated syndrome (CIS)?

Yes; she has MS

Yes; she has CIS because this is the first (and only) episode

No; more information is needed

No; other conditions in the differential diagnosis should be considered

This quiz is not accredited for CME.

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