Infants who miss the hepatitis B (HepB) birth dose vaccine are at risk for under-immunization by 18 to 24 months of age, a recent study found. The retrospective cohort included infants born over 1 year at an academic medical center. The “not vaccinated at birth” group consisted of all infants who did not receive the HepB birth dose vaccine by 7 days of life, while the “vaccinated at birth” group included infants who did receive the birth dose. The primary outcome was vaccination status at 18 months of age. Researchers found:
- Infants in the “not vaccinated at birth” group had lower vaccination rates.
- At 18 months, 44% of the “vaccinated at birth” group received all recommended vaccines vs 23% of the “not vaccinated at birth” group.
- >80% of the variability in vaccination completions were related to a single latent variable, the most likely being vaccine hesitancy or refusal.
Wilson P, Taylor G, Knowles J, et al. Missed hepatitis B birth dose vaccine is a risk factor for incomplete vaccination at 18 and 24 months. [Published online ahead of print October 4, 2018]. J Infect. doi:10.1016/j.jinf.2018.09.014.
This study shows how important that first parental exchange on immunizations is for achieving vaccination goals. When these parents are counseled on the hepatitis B immunization status, what information are they given? Many studies have demonstrated that protocols are important, but beyond that a clinician explaining why they feel the vaccine is necessary is important. I would imagine that most hospitals have the protocols in place, but do the clinicians take the time to discuss the importance of the hepatitis B vaccine for newborns both short- and long-term? —John Russell, MD
This Week's Must Reads
Do Vitamin D Supplements Prevent Cancer, CVD?, N Engl J Med; 2019 Jan 3; Manson, Cook, et al
Nonadherence to Cancer Screenings & Related Mortality, JAMA Intern Med; ePub 2018 Dec 28; Pierre-Victor, et al
Alcohol Consumption After Development of HF, JAMA Netw Open; ePub 2018 Dec 28; Sadhu, et al
Opioid-Involved Overdose Deaths in the US, MMWR; 2019 Jan 4; Scholl, Seth, et al
Assessing the Diet Quality of US Children, Am J Clin Nutrit; ePub 2018 Dec 29; Thomson, et al
Must Reads in Vaccines
Acellular Pertussis Vaccine Is Safe & Effective, JAMA Pediatr; 2018 Nov; Wood, Nolan, et al
Influenza and Pertussis Vaccination in Pregnancy, Vaccine; ePub 2018 Nov 3; Wilcox, Bottrell, et al
Influenza Vaccine Efficacy in High-Risk Patients, Vaccine; ePub 2018 Nov 9; Shang, Chung, et al
Childhood Vaccination Coverage Rates Compared, J Paediatr Child Health; ePub 2018 Nov 13; Baumann, et al
Measles Immunity After Vaccination in Children with HIV, Clin Infect Dis; ePub 2018 Nov 12; Mutsaerts, et al