HER2-Positive Breast Cancer
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Albina Kibirova, MD
Fellow, West Virginia University Cancer Institute, Department of Medicine, Section of Hematology and Oncology, Morgantown, WV

Samantha J. Hall, NP-C
West Virginia University Cancer Institute, Department of Medicine, Section of Hematology and Oncology, Morgantown, WV

Mohamad A. Salkeni, MD
Associate Professor of Medicine, West Virginia University Health Sciences Center, Department of Medicine, Section of Hematology and Oncology, Morgantown, WV

Question 1 of 6

A 41-year-old woman presents to the emergency department with progressive dyspnea on exertion, lower-extremity edema, and palpitations. On exam, the patient is noted to have bibasilar pulmonary crackles, a third heart sound, and 1+ lower-extremity pitting edema. Her past medical history is notable for stage II breast cancer treated with surgery, chemotherapy plus trastuzumab, and radiation.

Which of the following factors has not been found to be significantly linked to increased risk of trastuzumab-induced cardiomyopathy?

Coadministration of anthracycline

High body mass index

Low left ventricular ejection fraction before chemotherapy administration

Old age

Preexisting hyperlipidemia

Hospital Physician: Hematology/Oncology. 2018 May;13(3)

This quiz is not accredited for CME.

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