Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

Monetary support affects select prescribing, Mitchell AP et al. JAMA Intern Med. 2018 Apr 9. doi: 0.1001/jamainternmed.2018.0776

Best TKI options in ALL, Jabbour E et al. Clin Lymphoma Myeloma Leuk. 2018 18(4):257-65

2 approaches to diagnosing heparin-induced thrombocytopenia, Pishko A et al. Biennial summit of the Thrombosis & Hemostasis Societies of North America (THSNA) 2018, Abstract 103

Blinatumomab eliminates residual B-cell ALL, Gökbuget N et al. Blood. 2018 Apr 5;131(14):1522-31.

Aryl hydrocarbon receptor antagonist boosts cord blood engraftment, Wagner J et al. 2018 Bone Marrow Transplant Tandem Meetings, Abstract 4.

Leukemia, Myelodysplasia, Transplantation

New Choosing Wisely Guidance on BMT Released , Biol Blood Marrow Transplant; ePub 2018 Jan 19; Bhella, et al

Second Primary Malignancies in Patients with MM, Biol Blood Marrow Transplant; ePub 2018 Jan 12; Sahebi, et al

Read more in Leukemia, Myelodysplasia, Transplantation

Thrombosis

2 approaches to diagnosing heparin-induced thrombocytopenia, Pishko A et al. Biennial summit of the Thrombosis & Hemostasis Societies of North America (THSNA) 2018, Abstract 103

VTE prophylaxis unaddressed in acutely ill patients, Amin A et al. The biennial summit of the Thrombosis & Hemostasis Societies of North America 2018, Poster 51.

Read more in Thrombosis

Bleeding Disorders

Plasminogen replacement therapy in congenital plasminogen deficiency, Shapiro A et al. Blood 2018 131:1301-1310; doi: https://doi.org/10.1182/blood-2017-09-806729

Cochrane on Phytomedicines for Sickle Cell Disease , Cochrane; 2018 Feb 15; Oniyangi, Cohall, et al

Read more in Bleeding Disorders

Patient & Survivor Care

Monetary support affects select prescribing, Mitchell AP et al. JAMA Intern Med. 2018 Apr 9. doi: 0.1001/jamainternmed.2018.0776

Cochrane on Oxycodone for Cancer-Related Pain, Cochrane; 2017 Aug 22; Schmidt-Hansen, et al

Read more in Patient & Survivor Care

Breast Cancer

Statins and Survival in Patients with Cancer, JAMA Oncol; ePub 2017 Aug 22; Emilsson, et al

FDA Approves Faslodex for Certain Breast Cancers, AstraZeneca news release; 2017 Aug 28

Read more in Breast Cancer

CNS/Brain Cancer

FDA Approves First Biosimilar to Treat Cancer, FDA news release; 2017 Sep 14

Chemo Regimens for High-Grade Gliomas, Cochrane; 2017 Jul 26; Parasramka, Talari, et al

Read more in CNS/Brain Cancer