Children between the ages of 13-14 years appear to be most at risk for pertussis, suggests an analysis of a 2012 outlook that occurred in Wisconsin.
- Researchers compared the role of different age groups in propagating the 2012 outbreak by measuring the change in the groups’ proportion of detected cases of pertussis before and after the epidemic’s peak.
- The data suggests that children aged 13 to 14 years made the largest contribution to the outbreak’s ascent.
- Children ages 11-12, 7-8, and 9-10 contributed to the outbreak in descending order of magnitude.
- A more limited role was played by young children, older teens, and adults.
- The analysis revealed that the 5th dose of DTaP and Tdap protected against infection, with various age groups responding differently.
Goldstein E, Worby C, Lipsitch M. On the role of different age groups, and pertussis vaccines during the 2012 outbreak in Wisconsin. [Published online ahead of print April 16, 2018]. Open Forum Infect Dis. doi:10.1093/ofid/ofy082.
This Week's Must Reads
Global Burden of CVD in People Living with HIV, Circulation; ePub 2018 Jul 2; Shah, et al
Penicillin Allergy & Risk of MRSA and C. difficle, BMJ; ePub 2018 Jun 27; Blumenthal, et al
Does Sleep Debt Decrease with Age? , Sleep Health; ePub 2018 Jun 28; Fox, et al
Firearm Injuries in Children & Adolescents, Pediatrics; ePub 2018 Jul 2; Herrin, et al
Effects of Pulse Pressure & BP Tx Intensity on AEs, Am J Med; ePub 2018 Jun 22; Krishnaswami, et al
Must Reads in Vaccines
Does Chronic Kidney Disease Affect Vaccine Response?, PLoS One; 2018 Apr 16; Wall, et al
Zoster and Pneumococcal Vaccines Are Compatible , Am J Epidemiol; ePub 2018 Apr 11; Bruxvoort, et al
HPV Vaccine Proves Ineffective in HIV Patients, Clin Infect Dis; ePub 2018 Apr 5; Wilkin, et al
Age Matters During a Pertussis Outbreak, Open Forum Infect Dis; 2018 Apr 16; Goldstein, et al
Newer Vaccine Technologies Can Speed Response, JAMA; 2018 Apr 10; Graham, Mascola, et al