Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Lung Cancer Incidence in Young Men & Women

N Engl J Med; 2018 May 24; Jemal, et al

The age-specific incidence of lung cancer has generally decreased among both men and women aged 30 to 54 years in all races and ethnic groups in the US over the past 2 decades. This according to a study that examined the nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group (30-34, 35-39, 40-44, 45-49, and 50-54 years), year of birth (1945 to 1980), and calendar period of diagnosis (1995-1999, 2000-2004, 2005-2009, and 2010-2014). Researchers also examined the prevalence of cigarette smoking. They found:

  • The decline in age-specific incidence of lung cancer in men has been steeper than among women over the past 20 years.
  • The patterns of historically higher incidence rates among men than among women have reversed among non-Hispanic whites and Hispanics born since the mid-1960s.
  • The prevalence of cigarette smoking among women born since 1965 had approached, but generally not exceeded, the prevalence among men.
Citation:

Jemal A, Miller KD, Ma J, et al. Higher lung cancer incidence in young women than young men in the United States. N Engl J Med. 2018;378:1999-2009. doi:10.1056/NEJMoa1715907.

This Week's Must Reads

Antibiotic Use Among US Older Adults, BMJ; ePub 2018 Jul 27; Olesen, Barnett, et al

Healthy Behaviors & Reduced Risk of Obesity , Mayo Clin Proc; ePub 2018 Jul 27; Shook, et al

Modifiable Risk Factors in New BP Categories, Am J Med; ePub 2018 Jul 26; Gu, Yue, et al

Psychological Screening for Youth with Abdominal Pain, Pediatrics; ePub 2018 Jul 25; Cunningham, et al

Low-Calorie Sweetened Beverages & Cardiometabolic Health, Circulation; ePub 2018 Jul 30; Johnson, et al

Must Reads in Oncology

Mortality Due to Cirrhosis & Liver Cancer in the US, BMJ; ePub 2018 Jul 18; Tapper, Parikh

Viral Suppression & Decreased Cancer Risk, Ann Intern Med; ePub 2018 Jun 12; Park, et al

ACS Recommends CRC Screening at Age 45, CA Cancer J Clin; ePub 2018 May 30; Wolf, et al

Lung Cancer Incidence in Young Men & Women, N Engl J Med; 2018 May 24; Jemal, et al

Risk Prediction Models for Lung Cancer Screening , Ann Intern Med; ePub 2018 May 15; Katki, et al