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Interventions to Increase CRC Screening Rates

JAMA Intern Med; ePub 2018 Oct 15; Dougherty, et al

Fecal blood test (FBT) outreach and patient navigation were associated with increased colorectal cancer (CRC) screening rates in the US, a recent study found. The systematic review and meta-analysis included 73 randomized clinical trials (n = 366,766 patients) of US-based interventions in clinical settings designed to improve CRC screening test completion in average-risk adults. The primary outcome was completion of CRC screening. Among the findings:

  • Interventions that were associated with increased CRC screening completion rates compared with usual care included FBT outreach, patient navigation, patient education, patient reminders, clinician interventions of academic detailing, and clinician reminders.
  • Combinations of interventions were associated with greater increased than single components.
  • Repeated mailed FBTs with navigation were associated with increased annual FBT completion.


Dougherty MK, Brenner AT, Crockett SD, et al. Evaluation of interventions intended to increase colorectal cancer screening rates in the United States. A systematic review and meta-analysis. [Published online ahead of print October 15, 2018]. JAMA Intern Med. doi:10.1001/jamainternmed.2018.4637.