Clinical Edge

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Carotid endarterectomy appears safe for stroke patients within 14 days of IVT

Key clinical point: Carotid endarterectomy can be performed safely within 14 days of intravenous thrombolysis in stroke patients, but safety within 72 hours remains unclear.

Major finding: Based on a meta-analysis of 1,165 patients, the average interval from intravenous thrombolysis to carotid endarterectomy was 7.1 days, and the cumulative 30-day stroke and death rate was 4.1%.

Study details: The data come from an analysis of 21 reports including outcomes in 1,165 patients.

Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.


Brinster CJ et al. J Cardiovasc Surg. 2020 Apr. doi: 10.23736/S0021-9509.20.11179-0.