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Hidradenitis suppurativa linked to increased risk of nonalcoholic fatty liver disease

Key clinical point: Hidradenitis suppurativa (HS) is significantly associated with the risk of developing nonalcoholic fatty liver disease (NALFD) regardless of the presence of classic metabolic risk factors.

Major finding: Patients with HS had a significantly higher prevalence of NAFLD vs. controls (57.6% vs. 31.7%; P less than .001). Multivariable analysis confirmed an independent association between HS and NAFLD (odds ratio, 2.79; P = .001) even after adjustment for age, body mass index, hypertension, and hypertransaminasemia.

Study details: The findings are based on a cross-sectional study of 125 patients with HS and 120 controls.

Disclosures: The study received a grant from the Institute for Health and Biomedical Research (ISABIAL-FISABIO Foundation). Gregor B Jemec has been an investigator, a consultant, and an advisory board member for Abbvie and Novartis and has received unrestricted grants from Abbvie, Leo Pharma, and Novartis. José C Pascual has been an advisory board member for Abbvie. Rest of the authors declared no conflicts of interest.


González-Villanueva I et al. Acta Derm Venereol. 2020 Jul 29. doi: 10.2340/00015555-3597.