Key clinical point: A study showed no significant differences between the effects of levothyroxine and placebo on fatigability.
Major finding: The between-group difference of perceived physical fatigability for patients taking levothyroxine and placebo was 0.2 (95% confidence interval, –1.8 to 2.1; P = 0.88).
Study details: A randomized, placebo-controlled study including 230 adults.
Disclosures: The study was funded by the European Union FP7 and the Swiss National Science Foundation. Merck KGaA Darmstadt (Germany) provided levothyroxine and the placebo. Dr. Stuber has no conflicts of interest.
REPORTING FROM SGIM 2019
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Labeling of Selective Androgen Receptor Modulators, JAMA; 2017 Nov 28; Van Wagoner, Eichner, et al
Vitamin D & Glycemic Control in Patients with T2D, J Clin Endocrinol Metab; 2017 Sep 1; Mirhosseini, et al
Continuous Glucose Monitoring in Patients with T2D, Ann Intern Med; ePub 2017 Aug 22; Beck, et al