Key clinical point: Short-term opioid use is associated with acute respiratory exacerbation in adults with COPD.
Major finding: Opioid exposure in the prior 7 days was associated with an 80.8% increase in the odds of exacerbation (odds ratio, 1.81; 95% confidence interval, 1.60-2.05).
Study details: Analysis of Mississippi Medicaid administrative claims data including 1,354 beneficiaries and 1,972 exacerbation events
Disclosures: There was no funding for this study, and none of the researchers declared conflicts of interest.
Rong Y et al. Am J Epidemiol. 2019 Jul 30. doi: 10.1093/aje/kwz169.