Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Mortality Risk with Cigarette, Cigar, & Pipe Use

JAMA Intern Med; ePub 2018 Feb 19; Christensen, et al

Use of cigar, pipes, and cigarettes each confers significant mortality risks, a recent study concluded. The National Longitudinal Mortality Study includes 357,420 participants who reportedly exclusively using cigar, pipes, or cigarettes or reported never using any type of tobacco product. Main outcome measures included all-cause and cause-specific mortality as identified as the primary cause of death. Researchers found:

  • There were 51,150 recorded deaths during follow-up.
  • Exclusive current cigarette smokers (HR, 1.98) and exclusive current cigar smokers (HR, 1.20) had higher all-cause mortality risks than never tobacco users.
  • Exclusive current cigarette smokers (HR, 4.06), exclusive current cigar smokers (HR, 1.61), and exclusive current pipe smokers (HR, 1.58) had an elevated risk of dying from a tobacco-related cancer.
  • There was also a statistically significantly elevated risk of mortality from most examined causes of death among both current daily and nondaily cigarette smokers.

Citation:

Christensen CH, Rostron B, Cosgrove C, et al. Association of cigarette, cigar, and pipe use with mortality risk in the US population. [Published online ahead of print February 19, 2018]. JAMA Intern Med. doi:10.1001/jamainternmed.2017.8625.

This Week's Must Reads

Planning for a Universal Influenza Vaccine, J Infect Dis; ePub 2018 Feb 28; Erbelding, et al

Reevaluating the Approach to Shigella Vaccine , PLoS One; 2018 Mar 28; Porter, et al

2-Dose Varicella Vaccine in School-Age Children, J Pediatr Infect Dis Soc; 2018 Mar 7; Lopez, et al

A Genetically Altered Syncytial Virus Vaccine, J Infect Dis; 2018 Apr; McFarland, et al

Zoster Vaccine Proves Immunogenic in HIV, Clin Infect Dis; ePub 2018 Mar 26; Benson, et al