Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

CV Mortality Among Adults with Diabetes

Diabetes Care; ePub 2018 Aug 21; Cheng, et al

In adults with diabetes, major cardiovascular disease (CVD) mortality has declined, especially in men, a recent study found. Researchers used the National Health Interview Survey (1988-2014) with mortality follow-up through the end of 2015 to estimate nationally representative trends and disparities in major CVD, ischemic heart disease (IHD), stroke, heart failure (HF), and arrhythmia mortality among adults aged ≥20 years by diabetes status. They found:

  • Over a mean follow-up of 11.8 years from 1988 to 2015 of 677,051 adults, there were significant decreases in major CVD death in adults with and without diabetes except adults aged 20 to 54 years.
  • Among adults with diabetes, 10-year relative changes in mortality were significant for major CVD, IHD, and stroke, but not HF and arrhythmia.
  • Men with diabetes had larger decreases in CVD death than women with diabetes.


Cheng YJ, Imperatore G, Geiss LS, et al. Trends and disparities in cardiovascular mortality among U.S. adults with and without self-reported diabetes mellitus, 1988-2015. [Published online ahead of print August 21, 2018]. Diabetes Care. doi:10.2337/dc18-0831.

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