Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Latest CDC Guidelines for Hepatitis B Prevention

MMWR Recomm Rep; 2018 Jan 12, Schillie, et al

The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) recently published its latest recommendations on preventing hepatitis B virus infection in the US. They include the following:

  • All pregnant women should be tested for hepatitis B surface antigen (HbsAg).
  • Any pregnant woman who tests positive for the antigen should have a follow-up test done to measure hepatitis B virus DNA.
  • Any infant who is born to a woman who is HBV infected should receive the HepB vaccine and hepatitis B immunoglobin within 12 hours of birth.
  • This series should be followed by completion of the vaccine series and post-vaccination serologic testing.
  • CDC also recommends universal hepatitis B vaccination within 24 hours of birth followed by the vaccine series.
Citation:

Schillie S, Vellozzi C, Reingold A, et al. Prevention of hepatitis B virus infection in the United States: Recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2018;67(No. RR-1):1–31. doi:10.15585/mmwr.rr6701a1.

This Week's Must Reads

Intensive BP Control & Risk of Dementia, JAMA; ePub 2019 Jan 28; SPRINT MIND Investigators

Outpatient Care for Adults With Primary Care, JAMA Intern Med; ePub 2019 Jan 28; Levine, et al

Antibiotic Therapy in Patients with Asthma, JAMA Intern Med; ePub 2019 Jan 28; Stefan, et al

Outpatient Benzodiazepine Prescribing in US, JAMA Netw Open; 2019 Jan 25; Agarwal, et al

Reduction of Readmissions Through Primary Care, JAMA Netw Open; 2019 Jan 25; Wiest, et al

Must Reads in Vaccines

Influenza Vaccination Safety During Hospitalization, Mayo Clin Proc; ePub 2019 Jan 8; Tartof, et al

Acellular Pertussis Vaccine Is Safe & Effective, JAMA Pediatr; 2018 Nov; Wood, Nolan, et al

Influenza and Pertussis Vaccination in Pregnancy, Vaccine; ePub 2018 Nov 3; Wilcox, Bottrell, et al

Influenza Vaccine Efficacy in High-Risk Patients, Vaccine; ePub 2018 Nov 9; Shang, Chung, et al

Childhood Vaccination Coverage Rates Compared, J Paediatr Child Health; ePub 2018 Nov 13; Baumann, et al