Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Flu Vaccine for All Visitors to Pediatric ED?

Pediatrics; 2018 Jan 2; Hart, et al

Offering influenza vaccine to every eligible patient who walks into a pediatric emergency department (ED) may be cost effective, suggests a recent analysis that looked at 4 different hypothetical scenarios. A cost effectiveness analysis was performed from January 2016 to June 2017 to evaluate vaccine strategies at a tertiary urban freestanding pediatric ED. Investigators evaluated 4 scenarios: offering the influenza vaccine to all patients, to those aged younger than 5 years, to high risk patients of any age, or to no patients. They found:

  • Providing vaccines to everyone would have generated the lowest cost, at $114.45 per case of flu that was prevented.
  • This approach would have saved $33.51/case, when compared to the no vaccination strategy and resulted in 27 fewer cases of the infection per 1,000 patients.
  • Giving the vaccine to everyone was also the most cost-effective approach regardless of patients’ ages or risk status.

Hart RC, Stevenson MD, Smith MJ, et al. Cost-effectiveness of strategies for offering influenza vaccine in the pediatric emergency department. Pediatrics. 2018;172:e173879. doi:10.1001/jamapediatrics.2017.3879.

This Week's Must Reads

Intensive BP Control & Risk of Dementia, JAMA; ePub 2019 Jan 28; SPRINT MIND Investigators

Outpatient Care for Adults With Primary Care, JAMA Intern Med; ePub 2019 Jan 28; Levine, et al

Antibiotic Therapy in Patients with Asthma, JAMA Intern Med; ePub 2019 Jan 28; Stefan, et al

Outpatient Benzodiazepine Prescribing in US, JAMA Netw Open; 2019 Jan 25; Agarwal, et al

Reduction of Readmissions Through Primary Care, JAMA Netw Open; 2019 Jan 25; Wiest, et al

Must Reads in Vaccines

Influenza Vaccination Safety During Hospitalization, Mayo Clin Proc; ePub 2019 Jan 8; Tartof, et al

Acellular Pertussis Vaccine Is Safe & Effective, JAMA Pediatr; 2018 Nov; Wood, Nolan, et al

Influenza and Pertussis Vaccination in Pregnancy, Vaccine; ePub 2018 Nov 3; Wilcox, Bottrell, et al

Influenza Vaccine Efficacy in High-Risk Patients, Vaccine; ePub 2018 Nov 9; Shang, Chung, et al

Childhood Vaccination Coverage Rates Compared, J Paediatr Child Health; ePub 2018 Nov 13; Baumann, et al