Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Smoking cessation could delay or prevent rheumatoid arthritis

Key clinical point: Smoking cessation significantly reduces the risk and delays the onset of rheumatoid arthritis.

Major finding: Women who quit smoking more than 30 years ago have a 37% lower risk of seropositive rheumatoid arthritis than do those who quit recently.

Study details: Analysis of data from 230,732 women in the Nurses’ Health Study and NHS II.

Disclosures: The National Institutes of Health supported the study. No conflicts of interest were declared.


Liu X et al. Arthritis Care Res. 2019 Feb 21. doi: 10.1002/acr.23837.

Must Reads in Rheumatology

TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

List of medications linked to drug-induced lupus expands, Arnaud L et al. Ann Rheum Dis. 2019 Feb 4. doi: 10.1136/annrheumdis-2018-214598

Screening for Osteoporosis to Prevent Fractures, JAMA; ePub 2018 Jun 26; US Preventive Services Task Force

Psychological Interventions & Chronic Pain Reduction, JAMA Intern Med; ePub 2018 May 7; Niknejad, et al