Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Prednisolone scores for hand OA

Key clinical point: Prednisolone helps in acute flares of hand OA, probably more than NSAIDs.

Major finding: A total of 42 patients randomized to prednisolone 10 mg/day fell a mean of 21.5 mm at 6 weeks from a baseline visual analog hand pain score of 54 mm (out of a possible 100 mm), versus a drop of 5.2 mm from a baseline score of 53 mm among 46 randomized to placebo.

Study details: Double-blind, randomized, placebo-controlled trial

Disclosures: The lead investigator had no disclosures. The work was funded by the Dutch Arthritis Society.


Kroon F et al. Arthritis Rheumatol. 2019;71(suppl 10), Abstract 1760.