Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

PAP May Reduce Mortality in Patients with Obesity and Severe OSA

Key clinical point: Prescription of positive airway pressure may reduce all-cause and cardiovascular mortality.

Major finding: The adjusted hazard ratio of all-cause mortality was 0.38 for patients prescribed positive airway pressure therapy.

Study details: A multicenter, population-based cohort study of data for 392 participants in the Sleep Heart Health Study.

Disclosures: The Sleep Heart Health Study was supported by grants from the National Institutes of Health.


Lisan Q et al. JAMA Otolaryngol Head Neck Surg. 2019 Apr 11. doi: 10.1001/jamaoto.2019.0281.