Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Nucleic acid testing before PrEP urged to detect occult HIV

Key clinical point: HIV nucleic acid amplification testing should be routine before PrEP.

Major finding: Almost a third of patients who developed HIV while on PrEP had strains that were resistant to emtricitabine at time of diagnosis, compared with just 2% of those not on PrEP.

Study details: Review of 3,685 new HIV cases in New York.

Disclosures: There was no external funding, and the investigators didn’t have any disclosures.


Misra K et al. 2019 CROI, Abstract 107.