Clinical Edge

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Vitamin D Supplementation May Improve Ulcerative Colitis

Key clinical point: Vitamin D supplementation may reduce disease activity in some patients with ulcerative colitis (UC).

Major finding: Vitamin D levels were negatively correlated with ulcerative colitis disease activity index (UCDAI; rho = −0.713; P less than or equal to .001).

Study details: A double-blind, placebo-controlled trial involving 60 patients with active ulcerative colitis and vitamin D deficiency.

Disclosures: The investigators disclosed no external funding or conflicts of interest.


Ahamed R et al. J Clin Gastroenterol. 2019 Jul 24. doi: 10.1097/MCG.0000000000001233.