Key clinical point: Mannose-binding lectin and ficolin-2 are potential biomarkers for the development of liver cancer in chronic hepatitis C virus infection.
Major finding: Ficolin-2 and mannose-binding lectin were elevated at 1 and 3 years prior to hepatocellular carcinoma diagnosis, respectively,
Study details: A biochemical analysis of blood samples from the Trent HCV clinical cohort and commercial sources.
Disclosures: The study was funded by a split-site PhD scholarship between the University of Sulaimani (Iraq), and the University of Nottingham (England). The authors reported they had no conflicts.
Jalal PJ et al. Virology. 2019;530:99-106.