Key clinical point: A meta-analysis of evidence suggests no association between a diagnosis of dementia and PPI use.
Major finding: The incidence of dementia was not significantly increased among patients in the PPI-exposed group (OR, 1.08 (95% CI, 0.97-1.20; P = .18).
Study details: A meta-analysis of five studies comprising 472,933 patients.
Disclosures: The researchers reported having no financial disclosures.
REPORTING FROM DDW 2019