Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Ketamine tied to remission from suicidal ideation

Key clinical point: Serial ketamine infusions eliminated suicidal ideation in more than two-thirds of patients but at significantly higher doses than those recently approved for Janssen’s new nasal esketamine spray (Spravato).

Major finding: Among 144 patients, IV ketamine diminished suicidal ideation in 118 (82%) and eliminated them in 98 (68%).

Study details: Single-center review of 235 patients with treatment-resistant depression.

Disclosures: The report had no external funding, and Dr. Calabrese had no disclosures.

Citation:

REPORTING FROM APA 2019