Key clinical point: Interstitial lung abnormalities were significantly associated with moderate to severe acute exacerbation in adults with chronic obstructive pulmonary disorder.
Major finding: Over a 5-year follow-up period, patients with interstitial lung abnormalities had twice the risk of frequent exacerbation, compared with those without ILA (adjusted odds ratio, 2.03).
Study details: The data come from a retrospective study of 363 adults with chronic obstructive pulmonary disorder who received chest CT and longitudinal pulmonary function tests between January 2013 and December 2018.
Disclosures: The study received no outside funding. The researchers had no financial conflicts to disclose.
Lee TS et al. Chest. 2020 Aug 13. doi: 10.1016/j.chest.2020.08.017.