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Oral contraceptive use associated with smaller hypothalamic and pituitary volumes

Key clinical point: The hypothalamic volume of women taking oral contraceptives was about 6% smaller than naturally cycling women.

Major finding: Volumes of both the hypothalamus and pituitary were lower in women taking OCs compared with naturally cycling women (P = .006 and .007, respectively).

Study details: Prospective study using MRI and neurocognitive testing in 21 women on OCs and 29 naturally cycling women.

Disclosures: The authors reported no conflicts of interest and no external sources of funding.


Chen K et al. RSNA 2019. Presentation SSM-1904.