Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Statins may lower risk of colorectal cancer

Key clinical point: Statin use may lower the risk of colorectal cancer (CRC) in patients with or without inflammatory bowel disease (IBD).

Major finding: Patients with IBD who used statins had a 60% lower risk of CRC (pooled odds ratio, 0.40; 95% confidence interval, 0.19-0.86; P = .019).

Study details: A systematic review and meta-analysis of 52 studies involving 11,459,306 patients.

Disclosures: The investigators and Dr. Kaplan reported no relevant conflicts of interest.