Young adults with elevated blood pressure (BP), stage 1 hypertension, and stage 2 hypertension before age 40 years, as defined by the BP classification in the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, had significantly higher risk for subsequent cardiovascular disease (CVD) events compared to those with normal BP before age 40, a new study found. The prospective cohort study included 4,851 young adults (aged 18‒30 years) with CVD events as the primary outcome. Researchers found:
- Over a median follow-up of 18.8 years, 228 incident CVD events occurred.
- CVD incidence rates for normal BP, elevated BP, stage 1 hypertension, and stage 2 hypertension were 1.37, 2.74, 3.15, and 8.04 per 1,000 person-years, respectively.
- After multivariable adjustment, hazard ratios (HRs) for CVD events for elevated BP, stage 1 hypertension, and stage 2 hypertension vs normal BP were 1.67, 1.75, and 3.49, respectively.
Yano Y, Reis JP, Colangelo LA, et al. Association of blood pressure classification in young adults using the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline with cardiovascular events later in life. JAMA. 2018;320(17):1774–1782. doi:10.1001/jama.2018.13551.