Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Significant Increase in Low-Attenuation Coronary Plaques in Lupus

Key clinical point: Positive remodeling and low-attenuation, noncalcified plaques might be something to look for when assessing systemic lupus erythematosus cardiovascular risk.

Major finding: There was a mean of 458 low-attenuation, noncalcified plaques among lupus patients versus 42 among controls, a more than 900% difference (P less than .001)

Study details: Coronary CT angiography in 102 lupus patients and 100 healthy controls

Disclosures: The National Institutes of Health funded the work. The lead investigator didn’t report any relevant disclosures.


Stojan G et al. Lupus Sci Med. 2019;6[suppl 1]:A200, Abstract 274.