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Acute lymphoblastic leukemia can be successfully treated in the frail elderly

Key clinical point: Attenuated chemotherapy shows effectiveness in frail and elderly acute lymphoblastic leukemia patients.

Major finding: The complete remission rate was 54%, with the probability of overall survival at 7.6 months.

Study details: A series of 72 older and elderly frail patients with Philadelphia chromosome–negative acute lymphoblastic leukemia prospectively treated with very attenuated chemotherapy.

Disclosures: The study was supported by the CERCA Program/Generalitat de Catalunya and the Josep Carreras Leukemia Research Institute. The authors reported having no disclosures.


Ribera J-M et al. Clin Lymphoma Myeloma Leuk. 2020 Apr 5. doi: 10.1016/j.clml.2020.03.011.