Clinical Edge

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LAIV Doesn’t Increase Asthmatic Children’s Risk of Lower Respiratory Events

Key clinical point: Live attenuated influenza vaccine does not increase the risk of lower respiratory events in children with asthma, compared with inactivated influenza vaccine.

Major finding: The adjusted ratio of rate ratios was 0.74 for events within 21 days of vaccination and 0.77 for events within 42 days of vaccination.

Study details: A retrospective cohort study of 4,771 children with asthma or recurrent wheezing who received influenza vaccine.

Disclosures: The research was funded by a grant from the National Institute of Allergy and Infectious Diseases. The authors had no relevant financial disclosures.


Nordin JD et al. Vaccine. 2019 Jun 10. doi: 10.1016/j.vaccine.2019.05.081.