Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

HF Hospitalizations & Substance Abuse Disorders

Am J Med; ePub 2018 Dec 15; Snow, et al

Among patients hospitalized for heart failure (HF), tobacco or substance use disorders are more common among males, younger age groups, lower socioeconomic status, and select racial/ethnic minorities. This according to a recent study that calculated the proportion of primary HF hospitalizations in the 2014 National Inpatient Sample with tobacco or substance use disorders, accounting for demographic factors. Researchers found:

  • 15.5% of HF hospitalizations (n=152,965) in the US had documented tobacco (12.1%) or substance (6.2%) use disorder.
  • Female sex was associated with lower rates of tobacco and substance use disorder.
  • Tobacco or substance use disorders were more common among males and highest for hospitalization aged <55 years.
  • Enhanced screening for tobacco and substance use disorders in hospitalized HF patients may reveal opportunities for treatment and secondary prevention.


Snow SC, Fonarow GC, Ladapo JA, Washington DL, Hoggatt KJ, Ziaeian B. National rate of tobacco and substance use disorders among hospitalized heart failure patients. [Published online ahead of print December 15, 2018]. Am J Med. doi:10.1016/j.amjmed.2018.11.038.

This Week's Must Reads

Intensive BP Control & Risk of Dementia, JAMA; ePub 2019 Jan 28; SPRINT MIND Investigators

Outpatient Care for Adults With Primary Care, JAMA Intern Med; ePub 2019 Jan 28; Levine, et al

Antibiotic Therapy in Patients with Asthma, JAMA Intern Med; ePub 2019 Jan 28; Stefan, et al

Outpatient Benzodiazepine Prescribing in US, JAMA Netw Open; 2019 Jan 25; Agarwal, et al

Reduction of Readmissions Through Primary Care, JAMA Netw Open; 2019 Jan 25; Wiest, et al

Must Reads in Addiction Medicine

Opioid-Involved Overdose Deaths in the US, MMWR; 2019 Jan 4; Scholl, Seth, et al

HF Hospitalizations & Substance Abuse Disorders, Am J Med; ePub 2018 Dec 15; Snow, et al

Secondhand Smoke Exposure in Nonsmokers, MMWR; 2018 Dec 7; Tsai, Homa, et al

USPSTF: Screen Adults for Unhealthy Alcohol Use, JAMA; 2018 Nov 13; Curry, et al

Prevalence of E-Cigarette Use Among US Adults, Ann Intern Med; 2018 Oct 2; Mirbolouk, et al