Clinical Edge | MDedge Internal Medicine

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

Younger adults present with more advanced esophageal adenocarcinoma,

Osteoporosis prevalence in PsA similar to general population,

Mortality risks rise with age, infections, but not inhibitor status in persons with non-severe hemophilia A,

DOACs look safe in elective endoscopic procedures,

Anorexia and diarrhea top list of GI symptoms in COVID-19 patients,

FDA Actions

FDA Approves Steglatro for Adults with T2D, Pfizer news release; 2017 Dec 22

FDA Approves Ozempic for Treatment of T2D, Novo Nordisk news release; 2017 Dec 5

Read more in FDA Actions

Clinical Guidelines

USPSTF: Interventions to Avert Perinatal Depression, JAMA; 2019 Feb 12; US Preventive Services Task Force

PERT alerts improve pulmonary embolism outcomes, Benninghoff M. Critical Care Congress 2019, Abstract 490

Read more in Clinical Guidelines

Diversity in Medicine

Black patients less likely to receive H. pylori eradication testing,

Read more in Diversity in Medicine

Adolescent Medicine

Experts disagree with USPSTF’s take on pediatric blood pressure screening,

Alcohol problems linked to legal performance-enhancement products,

Read more in Adolescent Medicine

Rheumatology

Osteoporosis prevalence in PsA similar to general population,

Weight loss may be paramount lifestyle change in preventing gout,

Read more in Rheumatology

Rare Diseases

Childhood Hodgkin survivors have neurocognitive impairment,

ASSET extension supports abatacept as treatment for diffuse cutaneous systemic sclerosis,

Read more in Rare Diseases

Oncology

Younger adults present with more advanced esophageal adenocarcinoma,

Two different radiation boost strategies reduce local failures in NSCLC,

Read more in Oncology

Neurology

HIT-6 may help track meaningful change in chronic migraine,

Vascular dementia risk particularly high in type 2 diabetes,

Read more in Neurology

Obesity

Endoscopic intragastric balloon improved NASH parameters,

Autologous fecal microbiota transplantation helped maintain weight loss after ‘green’ Mediterranean diet,

Read more in Obesity

Women's Health

Long-term APBI cosmetic, toxicity data reported WBI has the edge Practice-confirming results,

Geography and behaviors linked to early-onset colorectal cancer survival in U.S. women,

Read more in Women's Health

Pain

Real acupuncture beat sham for osteoarthritis knee pain,

Appendix may be common site of endometriosis,

Read more in Pain

Preventive Care

Sedentary postmenopausal women have higher heart failure risk,

Don’t miss cardiovascular risk factors in transgender patients,

Read more in Preventive Care

Heartburn/Acid Reflux

PPIs associated with diabetes risk, but questions remain,

GERD: Endoscopic therapies may offer alternative to PPIs,

Read more in Heartburn/Acid Reflux

Transgender Health

Don’t miss cardiovascular risk factors in transgender patients,

Hormone therapy boosts body image in transgender youth,

Read more in Transgender Health

COVID-19 Updates

Anorexia and diarrhea top list of GI symptoms in COVID-19 patients,

COVID-19 vaccine found effective but doctors watching for reactions, adverse events,

Read more in COVID-19 Updates

Career

Cost of Physician Burnout Estimated at $4.6 Billion a Year,

Physician Groups Produce More Accurate Diagnoses than Individuals,

Read more in Career