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Differences in HPV Seroprevalence By Sex

Clin Infect Dis; ePub 2018 Nov 24; Lewis, et al

Human papillomavirus (HPV) 6/11/16/18 seroprevalence was comparable among gay/bisexual men who have sex with men (MSM) and females, and both groups had significantly higher seroprevalence than men who have sex with only women (MSW). This according to a recent study of unvaccinated, sexually experienced persons (aged 18‒59 years) in the US that compared the groups using data from the National Health and Nutrition Examination Survey from 2003‒2010. Seroprevalences were compared using prevalence ratios adjusted for sexual behavior (aPRs). Researchers found:

  • Seroprevalence in MSM, MSW, and females was 42.6%, 13.2%, and 37.1%, respectively.
  • Seroprevalence in MSM was comparable to females (aPR, 0.85) and higher than MSW (aPR ,2.72).
  • MSW had a significantly lower seroprevalence than females (aPR, 0.31).
  • Similar associations were observed in all sociodemographic subgroups.
  • Seroprevalence increased with number of lifetime sex partners in all groups.

Citation:

Lewis RM, Markowitz LE, Panicker G, Unger ER. Seroprevalence of human papillomavirus 6/11/16/18 among self-identified gay/bisexual men who have sex with men, men who have sex with women, and females, United States, 2003–2010. [Published online ahead of print November 24, 2018]. Clin Infect Dis. doi:10.1093/cid/ciy1002.

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