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Variability in Antifungal Utilization in the US

BMC Infect Dis; ePub 2018 Oct 3; Stultz, et al

In an analysis of variability in antifungal utilization in US hospitals among patient groups, specific associations for antifungal use were identified in adult and pediatric patient groups, but not in the neonatal group. Researchers analyzed antifungal use and compared utilization between patient groups. For the neonatal, pediatric, and adult patient groups, 54, 44, and 60 hospitals were included, respectively. Among the findings:

  • Total antifungal use was significantly lower in the neonatal patient group.
  • There were no specific associations identified with total antifungal days of therapy/1,000 patient days in the neonatal patient group.
  • In the pediatric patient group, admission to immunosuppressed service lines and total broad-spectrum antibiotic use were positively associated with total antifungal use.
  • In the adult patient group, admission to immunosuppressed service lines, total invasive fungal infections, and total broad-spectrum antibiotic use were positively associated with total antifungal use.

Citation:

Stultz JS, Kohinke R, Pakyz AL. Variability in antifungal utilization among neonatal, pediatric, and adult inpatients in academic medical centers throughout the United States of America. [Published online ahead of print October 3, 2018]. BMC Infect Dis. doi:10.1186/s12879-018-3410-4.