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Targeting parasitic histones may improve outcomes in cerebral malaria

Key clinical point: Targeting circulating parasitic histones may hold promise for patients with cerebral malaria (CM).

Major finding: Mean circulating histone concentrations were higher in children with retinopathy positive CM (22.6 mcg/ml) than in healthy controls (0.33 mcg/ml).

Study details: A retrospective analysis of patients with cerebral malaria and healthy controls.

Disclosures: The investigators declared no conflicts of interest.


Moxon et al. BSH 2019. Abstract OR-034.