Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Influenza Associated Outcomes in Pregnancy

J Infect Dis; ePub 2019 Jan 23; Prasad, et al

When compared with nonpregnant women, season influenza poses higher risks of hospitalization on pregnant women in all trimesters, a new study found. Researchers joined individual-level administrative datasets and active surveillance data to estimate influenza-association hospitalization and outpatient visit rates by pregnancy, postpartum, and trimester status. They found:

  • During 2012‒2015, 46 (17.5%) of 260 influenza-confirmed acute respiratory hospitalizations and 13 (4.4%) of 294 influenza-confirmed outpatient visits were among pregnant and postpartum women.
  • Pregnant and postpartum women experienced higher rates of influenza hospitalization compared with nonpregnant women overall and by trimester.
  • Hospitalization rates varied by influenza type and ethnicity among pregnant women.


Prasad N, Huang QS, Wood T, et al. Influenza associated outcomes among pregnant, post-partum, and non-pregnant women of reproductive age. [Published online ahead of print January 23, 2019]. J Infect Dis. doi:10.1093/infdis/jiz035.

Must Reads in Influenza

Influenza Vaccination Effectiveness in the US, Clin Infect Dis; ePub 2019 Feb 2; Rolfes, et al

Influenza Associated Outcomes in Pregnancy, J Infect Dis; ePub 2019 Jan 23; Prasad, et al

Influenza Effects in Patients with Heart Failure, JACC Heart Fail; ePub 2019 Jan 2; Panhwar, et al

IDSA Updates Seasonal Influenza Guidelines, Clin Infect Dis; ePub 2018 Dec 19; Uyeki, et al

Efficacy of Cell-Cultured & Egg-Based Influenza Vaccines, J Infect Dis; ePub 2018 Dec 18; Izurieta, et al