In the US, trends in hospitalization rates among pediatric bloodstream infections (BSIs) vary by pathogen and regionally, while overall BSI hospitalization rates did not significantly decline from 2009‒2016, a new study found. Researchers conducted a retrospective cohort study from 2009‒2016 utilizing demographic and microbiology data on inpatients aged <19 years using the Premier Healthcare Database. Hospitalization rate was the number of BSI-positive encounters per 1,000 admissions. They found:
- Among 1,809,751 inpatients encounters from 162 US hospitals, 5,340 (0.30%) had a positive BSI, with community-acquired infections (CAIs) the most common.
- BSI patients were more often aged 1‒5 years and had a complex chronic condition or central line compared to non-BSI patients.
- BSI hospitalization rate declined non-significantly over time.
- Among pathogens, E. coli, methicillin-sensitive Staphylococcus aureus, and Group A Streptococcus significantly increased for non-neonates.
Spaulding AB, Watson D, Dreyfus J, et al. Epidemiology of bloodstream infections in hospitalized children in the United States, 2009–2016. [Published online ahead of print December 9, 2018]. Clin Infect Dis. doi:10.1093/cid/ciy1030.
This Week's Must Reads
Must Reads in Healthcare-acquired Infections
Antibiotic Use and Hospital Onset CDI Infection, Clin Infect Dis; ePub 2019 Mar 1; Kazakova, et al
Decolonization Lowers Postdischarge Infection Risk, N Engl J Med; 2019 Feb 14; Huang, et al
30-Day Readmission After S. aureus Bacteremia, Clin Infect Dis; ePub 2019 Feb 11; Inagaki, et al
Bloodstream Infections in Hospitalized Children, Clin Infect Dis; ePub 2018 Dec 9; Spaulding, et al