Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Better Management of OPAT Can Reduce Readmissions

Clin Infect Dis; ePub 2018 Sep 21; Shah, et al

Infectious disease (ID) consultation among privately insured patients aged <65 years during outpatient parenteral antimicrobial therapy (OPAT) is associated with significant reductions in the rate of emergency department (ED) admission and 30-day readmission, a recent study found. Researchers analyzed inpatient acute-care stays in 2013 and 2014 that were followed by OPAT. Patients who received outpatient ID intervention (ID-led OPAT) were matched 1:1 with those who did not (Other OPAT). They found:

  • 8,200 observations were included in the final analytic sample.
  • Soft-tissue infection and osteomyelitis were the most common infections in the index event, each affecting >40% of individuals.
  • Those with ID-led OPAT had lower odds of ED admission or hospitalization over 30 days, relative to those with Other OPAT.
  • Accumulated healthcare payments totaled $1,488 less among those with ID-led OPAT.

Citation:

Shah A, Petrak R, Fliegelman R, et al. Infectious diseases specialty intervention is associated with better outcomes among privately insured individuals receiving outpatient parenteral antimicrobial therapy. [Published online ahead of print September 21, 2018]. Clin Infect Dis. doi:10.1093/cid/ciy674.

This Week's Must Reads

IDSA Updates Seasonal Influenza Guidelines, Clin Infect Dis; ePub 2018 Dec 19; Uyeki, et al

Efficacy of Cell-Cultured & Egg-Based Influenza Vaccines, J Infect Dis; ePub 2018 Dec 18; Izurieta, et al

Prevention of Influenza Hospitalization in US Adults, J Infect Dis; ePub 2018 Dec 14; Ferdinands, et al

Clinical & Virologic & Characteristics of Zika Virus Infection, Open Forum Infect Dis; ePub 2018 Dec 19; El Sahly, et al

Importations of Measles Virus in the US, J Infect Dis; ePub 2018 Dec 9; Lee, et al

Must Reads in Healthcare-acquired Infections

Bloodstream Infections in Hospitalized Children, Clin Infect Dis; ePub 2018 Dec 9; Spaulding, et al

Disparities and Risk Factors for Septicemia Deaths , Open Forum Infect Dis; ePub 2018 Nov 15; Kempker, et al

Predicting Severe Outcomes in US Norovirus Outbreaks, J Infect Dis; ePub 2018 Nov 15; Burke, et al

GI Microbiota Disruption with CRPA in ICU Patients, Clin Infect Dis; ePub 2018 Nov 1; Pettigrew, et al

Better Management of OPAT Can Reduce Readmissions, Clin Infect Dis; ePub 2018 Sep 21; Shah, et al