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CDC Updates Zika Guidance for Infants

MMWR; 2017 Oct 20; Adebanjo, Godfred-Cato, et al

The Centers for Disease Control and Prevention (CDC) has updated its interim guidance for US healthcare providers caring for infants with possible congenital Zika virus infections. The updated recommendations emphasize the importance for healthcare providers to assess risk of congenital Zika virus infections, to communicate closely with obstetrical providers, and to remain alert for any problems that may develop in infants without birth defects born to mothers with possible Zika virus exposure during pregnancy. The new guidance includes the following recommendations:

  • All infants born to mothers with possible Zika virus exposure during pregnancy should receive a standard evaluation at birth and at each subsequent well-child visit, including a comprehensive physical examination, age-appropriate vision screening and developmental monitoring and screening.
  • All infants should also undergo newborn hearing screen at birth.
  • Specific guidance for laboratory testing and clinical evaluation are provided for 3 clinical scenarios in the setting of possible maternal Zika virus exposure: 1) infants with clinical findings consistent with congenital Zika syndrome regardless of maternal testing results, 2) infants without clinical findings consistent with congenital Zika syndrome who were born to mothers with laboratory evidence of possible Zika virus infections, and 3) infants without clinical findings consistent with congenital Zika syndrome born to mothers without laboratory evidence of possible Zika virus infection.
  • Infants in the first 2 scenarios should receive further testing and evaluation for Zika virus; further testing is not recommended for the third group.

Citation:

Adebanjo T, Godfred-Cato S, Viens L, et al. Update: Interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection—United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017;66:1089–1099. doi:10.15585/mmwr.mm6641a1.