Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Short-Term Statin Use Linked to Risk of Skin and Soft Tissue Infections

Key clinical point: Statin users are at increased risk for SSTIs, but the risk was independent of diabetes.

Major finding: Use of statins was significantly associated with an increased risk of SSTIs at 91 days (adjusted sequence ratio, 1.40).

Study details: The data come from a sequence symmetry analysis of prescription claims for 2001 to 2011 from the Australian Department of Veterans’ Affairs.

Disclosures: The study was supported in part by the Australian Government Research Training Program Scholarship, the Curtin Health Innovation Research Institute (CHIRI) Biosciences Research Precinct Core Facility, and the School of Pharmacy and Biomedical Sciences (Curtin University). The researchers had no financial conflicts to disclose.


Ko H et al. Br J Clin Pharmacol. 2019 Oct 9. doi: 10.1111/bcp.14077.