Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

S. Epidermidis Protection Against S. Aureus Colonization

Open Forum Infect Dis; ePub 2016 Nov 1; Sullivan, et al

There was a lower prevalence of S. aureus and methicillin-resistant Staphylococcus aureus (MRSA) colonization than previously reported in people living with HIV (PLWH), according to a recent cross-sectional study of an inner city outpatient population. The study determined the prevalence and molecular epidemiology of S. aureus colonization in 93 PLWH attending an urban HIV clinic. Researchers found:

  • Most participants had well-controlled HIV infection.
  • 36 (39%) individuals were colonized with S. aureus at 1 or more body sites, including 6 (6%) with MRSA.
  • Regular gym use was a risk factor for S. aureus but not MRSA carriage.
  • S. epidermidis was present in almost all individuals (n=84), predominantly in the nares (n=66).
  • The odds of S. aureus colonization were 80% less if S. epidermidis was present (adjusted OR, 0.20).

Citation:

Sullivan SB, Kamath S, McConville T, et al. S. epidermidis protection against S. aureus colonization in people living with HIV in an inner city outpatient population: A cross-sectional study. [Published online ahead of print November 1, 2016]. Open Forum Infect Dis. doi:10.1093/ofid/ofw234.