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S. Epidermidis Protection Against S. Aureus Colonization

Open Forum Infect Dis; ePub 2016 Nov 1; Sullivan, et al

There was a lower prevalence of S. aureus and methicillin-resistant Staphylococcus aureus (MRSA) colonization than previously reported in people living with HIV (PLWH), according to a recent cross-sectional study of an inner city outpatient population. The study determined the prevalence and molecular epidemiology of S. aureus colonization in 93 PLWH attending an urban HIV clinic. Researchers found:

  • Most participants had well-controlled HIV infection.
  • 36 (39%) individuals were colonized with S. aureus at 1 or more body sites, including 6 (6%) with MRSA.
  • Regular gym use was a risk factor for S. aureus but not MRSA carriage.
  • S. epidermidis was present in almost all individuals (n=84), predominantly in the nares (n=66).
  • The odds of S. aureus colonization were 80% less if S. epidermidis was present (adjusted OR, 0.20).


Sullivan SB, Kamath S, McConville T, et al. S. epidermidis protection against S. aureus colonization in people living with HIV in an inner city outpatient population: A cross-sectional study. [Published online ahead of print November 1, 2016]. Open Forum Infect Dis. doi:10.1093/ofid/ofw234.