Clinical Edge

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Patient Follow-Up in OPAT & Readmissions

Clin Infect Dis; ePub 2019 Feb 27; Palms, et al

Using a predictive model for all-cause 30-day readmission among patients discharged on outpatient parenteral antimicrobial therapy (OPAT), researchers found that close follow-up at the infectious disease clinic was a preventive factor for readmission. A retrospective chart review was performed and logistic regression used to assess OPAT and other outpatient clinic follow-up in conjunction with age, sex, pathogen, diagnosis, discharge medications, planned length of therapy, and Charlson comorbidity score. Researchers hypothesized that at least 1 follow-up visit at the Emory OPAT clinic would reduce the risk for hospital readmission within 30 days. They found:

  • Among 755 patients, 137 (18%) were readmitted within 30 days.
  • Most patients (73%) received outpatient follow-up care within 30 days of discharge or prior to readmission, including 52% of patients visiting the OPAT clinic.
  • A follow-up OPAT clinic visit was associated with lower readmission compared to those who had no follow-up visit (OR, 0.10).


Palms D, Jacob JT. Close patient follow-up among patients receiving outpatient parenteral antimicrobial therapy. [Published online ahead of print February 27, 2019]. Clin Infect Dis. doi:10.1093/cid/ciz150.