Key clinical point: An antibiotic-eluting envelope significantly reduced the risk of infection with CIED implantation.
Major finding: Antibiotic-eluting envelope in CIED implantation is associated with a 40% reduction in the risk of infection.
Study details: Randomized trial in 6983 patients.
Disclosures: The study was supported by Medtronic. Twenty-four authors declared institutional funding or research grants from Medtronic, thirteen declared fees, consultancies and other support from private industry outside the submitted work. Three authors were employees of Medtronic.
Tarakji K et al. NEJM, 2019, March 17. DOI: 10.1056/NEJMoa1901111.
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