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Physical Activity and Cognitive Health in HIV

J Infect Dis; ePub 2018 Aug 18; Chow, et al

Physical activity may have a greater positive impact on cognitive health in women than in men living with human immunodeficiency virus (HIV) infection, a new study found. Researchers investigated whether associations between cardiometabolic risk factors and prevalent HIV-associated cognitive impairment differ by sex. Separate logistic regression models were constructed for women and men at entry into a prospective study of older persons with HIV (PWH) to assess the association of cardiometabolic and other risk factors with cognitive impairment. They found:

  • 988 participants were included in the study (20% women).
  • Women had higher total cholesterol, hemoglobin A1c, and body mass index (BMI) compared with men and were less physically active.
  • In multivariable models, physical activity was associated with lower odds of cognitive impairment in women (OR, 0.35), but not men.

Citation:

Chow FC, Makanjuola A, Wu K, et al. Physical activity is associated with lower odds of cognitive impairment in women but not men living with HIV infection. [Published online ahead of print August 18, 2018]. J Infect Dis. doi:10.1093/infdis/jiy503.

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