While Toxocara seroprevalence estimates in the US were lower in 2011-2014 than from a previous study from 1988-1994, seropositivity risk factors remained unchanged, a recent study found. The study used a multiplex bead based assay with purified Toxocara canis antigen to estimate Toxocara antibody seroprevalence in a serum of 13,509 persons aged ≥6 years from the National Health and Nutrition Examination Survey (NHANES), 2011-2014, and identified seropositivity risk factors. Researchers found:
- The age standardized estimate of Toxocara seroprevalence was 5.0%; this was lower than previously reported.
- Risk factors for seropositivity from multiple logistic regression were older age, non-Hispanic black race/Hispanic origin vs non-Hispanic white, male sex, living below the poverty level, households with ≥0.5 persons per room, less than college education, and birth outside the US.
Liu EW, Chastain HM, Shin SH, et al. Seroprevalence of antibodies to Toxocara species in the United States and associated risk factors, 2011- 2014. [Published online ahead of print September 4, 2017]. Clin Infect Dis. doi:10.1093/cid/cix784.
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