Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

STIs Among People with HIV & Transmission Risk

Open Forum Infect Dis; ePub 2018 Jan 24; Lucar, et al

Sexually transmitted infections (STIs) are highly prevalent among persons infected with HIV and receiving care in Washington, DC, and HIV transmission risk is considerable at the time of STI diagnosis, a recent study found. Researchers evaluated the incidence and demographic factors associated with chlamydia, gonorrhea, and syphilis among HIV-infected persons enrolled at 13 DC cohort sites from 2011 to 2015, as well as assessing covariates of risk for incident STIs and estimating HIV transmission risk. They found:

  • 6.7% (451/6,672) participants developed an incident STI during a median follow-up of 32.5 months.
  • 30% of participants had ≥2 STI episodes.
  • Incidence rate of any STI was 3.8 cases per 100 person-years and was highest among those aged 18 to 34 years (10.8).
  • Hispanic ethnicity, MSM risk, and higher nadir CD4 counts strongly associated with STIs.
  • Among those with STI, 41.8% had a detectable viral load (VL) within 1 month of STI diagnosis, and 14.6% had a VL ≥1,500 copies/mL.

Citation:

Lucar J, Hart R, Rayeed N, et al. Sexually transmitted infections among HIV-infected individuals in the District of Columbia and estimated HIV transmission risk: Data from the DC cohort. [Published online ahead of print January 24, 2018]. Open Forum Infect Dis. doi:10.1093/ofid/ofy017.

This Week's Must Reads

Carbapenem Resistance in Healthcare Settings, Open Forum Infect Dis; ePub 2018 Sep 21; McCann, et al

UATs for SP and LP in Community-acquired Pneumonia, Clin Infect Dis; ePub 2018 Sep 28; Bellew, et al

Better Management of OPAT Can Reduce Readmissions, Clin Infect Dis; ePub 2018 Sep 21; Shah, et al

Low Plasma 25(OH)D and Risk of Sepsis, Open Forum Infect Dis; ePub 2018 Sep 18; Kempker, et al

Long-Acting Opioid Use & Risk of Infections, Clin Infect Dis; ePub 2018 Sep 15; Wiese, et al

Must Reads in HIV

Parenting Desires in Men & Women Living with HIV, Open Forum Infect Dis; ePub 2018 Sep 15; Cohn, et al

Mobile Health Intervention for PrEP in Young MSM, Clin Infect Dis; ePub 2018 Sep 15; Liu, et al

Food Insecurity & Inflammation in Women Living with HIV, J Infect Dis; ePub 2018 Aug 27; Leddy, et al

Racial and Ethnic Disparities in HIV Care, Clin Infect Dis; ePub 2018 Aug 31; Desir, et al

Testing for HIV Drug Resistance , Clin Infect Dis; ePub 2018 Jul 20; Günthard, et al