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Chronic Opioid Therapy in HIV-Infected Patients

Clin Infect Dis; ePub 2018 May 31; Colasanti, et al

Among people living with HIV (PLHIV) on chronic opioid therapy (COT), opioid misuse and awareness of the addictive potential of COT are common, yet monitoring practices were not concordant with guidelines. Researchers assessed opioid risk behaviors, perceptions of risk, opioid monitoring and associated Current Opioid Misuse Measure (COMM) scores of PLHIV on COT. COT was defined as ≥3 opioid prescriptions ≥21 days apart in the past 6 months. They found:

  • 166 participants on COT were included (66% male, 72% black, median age 54 years).
  • The COMM score was high in 43% of participants.
  • 30% had an opioid treatment agreement, 66% a urine drug test (UDT), and 12% were on a pill count.
  • 90% acknowledged opioids can be addictive.
  • Patients who received monitoring practices reported high satisfaction.


Colasanti J, Lira MC, Cheng DM, et al. Chronic opioid therapy in HIV-infected patients: Patients’ perspectives on risks, monitoring and guidelines. [Published online ahead of print May 31, 2018]. Clin Infect Dis. doi:10.1093/cid/ciy452.

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